LOUISVILLE, Ky. (AP) -- Sisters Jude and Shoni Schimmel scored 12 points each to lead No. 7 Louisville in a 76-42 victory over Eastern Kentucky on Wednesday night.
Monique Reid added 11 points as all 11 players scored for the Cardinals (8-0), who started slow before overwhelming the Lady Colonels.
Jade Barber had 11 points and 10 rebounds to lead Eastern Kentucky (3-3), and Jalisa Bryant added 10 points, all in the first half.
Two 3-pointers by Bryant gave EKU a 6-0 lead as Louisville was scoreless for the first 3:47.
Bria Smith hit the first of two free throws to get the Cardinals on the scoreboard, starting a 19-0 run before Bryant's third 3-pointer of the half pulled the Lady Colonels to 19-9 with 8:36 remaining in the opening half.
Eastern Kentucky made just two free throws the rest of the half and trailed 39-11 at the break.
The Cardinals missed their first 11 shots before Reid's basket on three-point play on a post move gave them their first field goal nearly six minutes into the game. It was the first time in five games that Louisville trailed.
The Cardinals won three games in the Puerto Vallarta, Mexico from Nov. 20-22 to win the Hardwood Tournament of Hope before Monday's 79-61 win at Tennesee-Martin.
The Cardinals' defense sparked the first-half rally, scoring 22 points off 17 turnovers and holding EKU to just 14 percent shooting. It was the fifth time Louisville has held an opponent under 50 points this season.
EKU turned the ball over just the seven times in the second half and the Cardinals only outscored the Colonels 37-31 after the break. Barber's layup with 13:33 left cut Louisville lead to 46-25, the closest margin in the second half.
EKU lost its third straight after dropping games against Florida State and Wisconsin-Milwaukee in the San Juan Shootout in Puerto Rico during the Thanksgiving week.
Louisville's win comes before an in-state matchup of top 10 teams. No. 9 Kentucky visits on Sunday.