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CLEVELAND -- Josh Reddick homered twice, including a grand slam, and drove in a career-high six runs, and Josh Donaldson added a three-run shot in the Oakland Athletics' 11-1 win over the Cleveland Indians on Friday night.
Reddick's second career grand slam and Donaldson's homer sparked an eight-run second inning. Reddick added a two-run homer in the seventh.
Sonny Gray (5-1) allowed one run and two hits with nine strikeouts in six innings for Oakland, which has won seven of eight.
Both homers in Oakland's biggest inning of the season came off Zach McAllister (4-3), who struck out the side in the first, but retired only one batter in the second for the shortest outing of his career.
Reddick came into Friday in an 8-for-43 skid over his last 13 games.
Nick Swisher's solo homer in the first put Cleveland ahead, but Oakland sent 11 men to the plate in the second, with the first five reaching base. Brandon Moss doubled past Swisher and took third on Yoenis Cespedes' single. Lowrie's single got the Athletics even and Derek Norris walked to load the bases. Reddick followed by hitting a 1-0 pitch into the seats in right.
Coco Crisp and John Jaso drew one-out walks before Donaldson drove a 3-2 pitch into the home run porch in left field. The ball landed hit off a souvenir stand and traveled an estimated 410 feet.
Indians manager Terry Francona pulled McAllister for left-hander Kyle Crockett, who was making his major league debut. Gray played catch with Jaso in front of Oakland's dugout to keep loose during the pitching change.
Gray was in control other than allowing Swisher's homer. Michael Brantley singled with two outs in the third. The right-hander retired the final eight hitters, including five strikeouts.
Gray pitched six scoreless innings and struck out seven in a no-decision against the Indians on opening day. He's 3-0 on the road and 4-0 in night games.
Reddick's second home run came off Carlos Carrasco, giving him five multi-homer games in his career.
Lowrie drove in two runs, including a leadoff homer in the third, while Donaldson has homered in three straight games.
McAllister allowed eight runs in 113 innings and threw 38 pitches in the second, in which he gave up two homers, two singles, a double and three walks. The right-hander hasn't won since April 21, a stretch of five starts.
Athletics 11, Indians 1
Crisp cf2100Bourn cf3000
Gentry ph-cf1010Aviles cf1000
Jaso dh4100Swisher 1b4111
Dnldsn 3b4113Brantly lf4010
Callasp ph-3b1010CSantn 3b-c4000
Moss 1b-lf4110DvMrp rf4010
Cespds lf4120ACarer ss2000
Blanks ph-1b1010YGoms c3000
Lowrie ss5222Aguilar 3b1000
DNorrs c4220Chsnhll dh1000
Reddck rf4226JRmrz 2b3000
Totals 38 11 13 11Totals30131
E-Swisher (5), C.Santana (4). DP-Cleveland 3. LOB-Oakland 5, Cleveland 6. 2B-Moss (7), Cespedes (11). HR-Donaldson (10), Lowrie (3), Reddick 2 (4), Swisher (3).
Umpires-Home, Mike Estabrook; First, Jerry Layne; Second, Tom Woodring; Third, Mike DiMuro.
T-3:07. A-21,389 (42,487).